Overview

  • Product name
    Anti-NMDAR2A antibody [A12W]
    See all NMDAR2A primary antibodies
  • Description
    Rabbit monoclonal [A12W] to NMDAR2A
  • Specificity
    Recognizes NMDAR2A
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Tagged fusion protein corresponding to amino acids 1265-1464 of mouse NMDAR2A

  • Positive control
    • Rat brain membrane lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab77980 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Detects a band of approximately 170 kDa (predicted molecular weight: 165 kDa).

Target

  • Function
    NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
  • Sequence similarities
    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2A/GRIN2A subfamily.
  • Cellular localization
    Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • EPND antibody
    • FESD antibody
    • GluN2A antibody
    • Glutamate [NMDA] receptor subunit epsilon-1 antibody
    • Glutamate receptor antibody
    • Glutamate receptor ionotropic N methyl D aspartate 2A antibody
    • GRIN 2A antibody
    • GRIN2A antibody
    • hNR2A antibody
    • LKS antibody
    • N methyl D aspartate receptor channel, subunit epsilon 1 antibody
    • N Methyl D Aspartate Receptor Subtype 2A antibody
    • N methyl D aspartate receptor subunit 2A antibody
    • N-methyl D-aspartate receptor subtype 2A antibody
    • NMDA receptor subtype 2A antibody
    • NMDAR 2A antibody
    • NMDAR2A antibody
    • NMDE1_HUMAN antibody
    • NR2A antibody
    • OTTHUMP00000160135 antibody
    • OTTHUMP00000174531 antibody
    see all

Images

  • Anti-NMDAR2A antibody [A12W] (ab77980) at 1/10000 dilution + Rat brain microsomal preparation

    Secondary
    Goat anti-rabbit secondary antibody conjugated to HRP
    Developed using the ECL technique

    Predicted band size : 165 kDa
    Observed band size : 165 kDa

References

This product has been referenced in:
  • Liu H  et al. The distinct role of NR2B subunit in the enhancement of visual plasticity in adulthood. Mol Brain 8:49 (2015). WB ; Mouse . Read more (PubMed: 26282667) »
  • Ghafari M  et al. NMDA-complexes linked to spatial memory performance in the Barnes maze in CD1 mice. Behav Brain Res : (2011). WB ; Mouse . Read more (PubMed: 21377497) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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