Overview

  • Product nameAnti-NMDAR2C (phospho S1096) antibody
    See all NMDAR2C primary antibodies
  • Description
    Rabbit polyclonal to NMDAR2C (phospho S1096)
  • SpecificitySpecific for the NR2C subunit of the NMDA receptor phosphorylated at Ser1096. Immunolabeling is blocked by preadsorption of antibody with the phospho-peptide that was used to generate the antibody but not by the corresponding dephospho-peptide.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Cow, Dog, Human, Non Human Primates
  • Immunogen

    Synthetic peptide corresponding to Rat NMDAR2C (C terminal) (phospho S1096).
    Database link: Q00961

  • Positive control
    • Mouse brain lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: None
    Constituents: 50% Glycerol, 100µg/ml BSA, 150 mM Sodium chloride, 10mM HEPES, pH 7.5
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPrepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 135 kDa.

Target

  • FunctionNMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
  • Tissue specificityMainly expressed in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas.
  • Sequence similaritiesBelongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2C/GRIN2C subfamily.
  • Cellular localizationCell membrane. Cell junction, synapse, postsynaptic cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GluN2C antibody
    • Glutamate [NMDA] receptor subunit epsilon-3 antibody
    • Glutamate Receptor Ionotropic N Methyl D Aspartate 2C antibody
    • Glutamate receptor ionotropic, NMDA 2C antibody
    • Glutamate receptor, ionotropic, N methyl D aspartate 2C antibody
    • Grin2c antibody
    • N Methly D Aspartate Receptor Channel Subunit Epsilon 3 antibody
    • N Methyl D Aspartate Receptor Subtype 2C antibody
    • N methyl D aspartate receptor subunit 2C antibody
    • N-methyl D-aspartate receptor subtype 2C antibody
    • NMDAR2C antibody
    • NMDE3_HUMAN antibody
    • NR2C antibody
    • OTTHUMP00000041930 antibody
    see all

Anti-NMDAR2C (phospho S1096) antibody images

  • All lanes : Anti-NMDAR2C (phospho S1096) antibody (ab106569) at 1/1000 dilution

    Lane 1 : Mouse brain lysate
    Lane 2 : Mouse brain lysate with immunoreactivity blocked by preadsorption with the phospho-peptide


    Predicted band size : 135 kDa

References for Anti-NMDAR2C (phospho S1096) antibody (ab106569)

This product has been referenced in:
  • Chen BS & Roche KW Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C. Neuron 62:471-8 (2009). Read more (PubMed: 19477150) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"