Overview

  • Product nameAnti-NMDAR3A + 3B antibody
  • Description
    Mouse monoclonal to NMDAR3A + 3B
  • SpecificityThis antibody recognizes NMDAR subunits NR3A and NR3B. It does not cross react with subunits NR1 or NR2AD.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Fusion protein, corresponding to amino acids 780-914 from the intracellular IIIIV loop of Human NR3A + NR3B.

  • General notes


    Two new subunits of the NMDA subtype of glutamate receptor (NMDAR) have been identified, NR3A and NR3B, with NR3B likely being the final member of the NMDAR family. These subunits show high sequence homology, although different distribution patterns: NR3B is expressed predominately in motor neurons, while NR3A is more widely distributed. When expressed in Xenopus oocytes, NR3A or NR3B assemble with NR1 to form excitatory glycine receptors that are unaffected by glutatmate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • Primary antibody notesTwo new subunits of the NMDA subtype of glutamate receptor (NMDAR) have been identified, NR3A and NR3B, with NR3B likely being the final member of the NMDAR family. These subunits show high sequence homology, although different distribution patterns: NR3B is expressed predominately in motor neurons, while NR3A is more widely distributed. When expressed in Xenopus oocytes, NR3A or NR3B assemble with NR1 to form excitatory glycine receptors that are unaffected by glutatmate.
  • ClonalityMonoclonal
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab2639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 10 µg/ml. Predicted molecular weight: 120-133 kDa.

Target

References for Anti-NMDAR3A + 3B antibody (ab2639)

ab2639 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"