The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).
1/50 - 1/100.
FunctionMajor role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
Sequence similaritiesBelongs to the NDK family.
Developmental stagePreferentially expressed at early stages of myeloid differentiation of highly purified CD34+ cells.