Overview

  • Product name
    NNC 55-0396 dihydrochloride
  • Description
    Highly selective T-type Ca2+ channel blocker
  • Biological description
    Highly selective T-type Ca2+ channel blocker. IC50 values are 6.8 and >100 μM for Cav3.1 T-type channels and HVA currents, respectively. Crosses the blood-brain barrier.
  • Purity
    > 99%

Properties

  • Chemical name
    (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl cyclopropanecarboxylate dihydrochloride
  • Molecular weight
    564.57
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C30H38FN3O2.2HCl
  • CAS Number
    357400-13-6
  • Storage instructions
    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

ab120265 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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