Overview

  • Product name
    Anti-NNT1 antibody (Biotin)
    See all NNT1 primary antibodies
  • Description
    Rabbit polyclonal to NNT1 (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Highly pure (>98%) recombinant human NNT1

Properties

  • Form
    Lyophilised:Centrifuge vial prior to opening. Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • Purification notes
    ab83408 is affinity purified and sterile filtered.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab83408 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant human NNT1.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 25 kDa.

Target

  • Function
    Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor.
  • Tissue specificity
    Expressed predominantly in lymph nodes, spleen, peripheral blood lymphocytes, bone marrow, and fetal liver.
  • Involvement in disease
    Defects in CLCF1 are the cause of cold-induced sweating syndrome type 2 (CISS2) [MIM:610313]. Cold-induced sweating syndrome (CISS) is an autosomal recessive disorder characterized by profuse sweating induced by cool surroundings (temperatures of 7 to 18 degrees Celsius). Additional abnormalities include a high-arched palate, nasal voice, depressed nasal bridge, inability to fully extend the elbows and kyphoscoliosis.
  • Sequence similarities
    Belongs to the IL-6 superfamily.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • B cell stimulating factor 3 antibody
    • B-cell-stimulating factor 3 antibody
    • BSF 3 antibody
    • BSF-3 antibody
    • BSF3 antibody
    • Cardiotrophin like cytokine antibody
    • Cardiotrophin like cytokine factor 1 antibody
    • Cardiotrophin-like cytokine factor 1 antibody
    • CISS 2 antibody
    • CISS2 antibody
    • CLC antibody
    • CLCF 1 antibody
    • Clcf1 antibody
    • CLCF1_HUMAN antibody
    • Cold induced sweating syndrome 2 antibody
    • CRLF 1 associated cytokine like factor 1 antibody
    • CRLF1 associated cytokine like factor 1 antibody
    • Neurotrophin 1 antibody
    • Neurotrophin 1/B cell stimulating factor 3 antibody
    • Neurotrophin1 antibody
    • NNT 1 antibody
    • NNT-1 antibody
    • Novel neurotrophin 1 antibody
    • Novel neurotrophin-1 antibody
    • NR 6 antibody
    • NR6 antibody
    see all

References for Anti-NNT1 antibody (Biotin) (ab83408)

ab83408 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab83408.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up