Overview

  • Product name
    Anti-Nogo B receptor antibody
    See all Nogo B receptor primary antibodies
  • Description
    Rabbit polyclonal to Nogo B receptor
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide corresponding to amino acids 64-74 (RNRRHHRHPRG) of human Nogo-B receptor (NgBR) was used as immunogen. This immunogen sequence is within the 93 amino acid putative ectodomain of the NgBR.

  • Positive control
    • Human, mouse and rat brain tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab47080 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 32 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.
      Essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery.
    • Pathway
      Protein modification; protein glycosylation.
    • Sequence similarities
      Belongs to the UPP synthase family.
    • Cellular localization
      Endoplasmic reticulum membrane. Colocalizes with Nogo-B during VEGF and wound healing angiogenesis.
    • Information by UniProt
    • Database links
    • Alternative names
      • C6orf68 antibody
      • MGC:7199 antibody
      • NgBR antibody
      • NGBR_HUMAN antibody
      • Nogo-B receptor antibody
      • Nuclear undecaprenyl pyrophosphate synthase 1 homolog antibody
      • nus1 antibody
      • TANGO14 antibody
      • Transport and golgi organization 14 homolog antibody
      see all

    Images

    • All lanes : Anti-Nogo B receptor antibody (ab47080) at 2 µg/ml

      Lane 1 : Human brain tissue lysate
      Lane 2 : Mouse brain tissue lysate
      Lane 3 : Rat brain tissue lysate


      Predicted band size : 51 kDa
      Observed band size : 32 kDa (why is the actual band size different from the predicted?)

    References

    ab47080 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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