WBmore details Unsuitable for:
Flow Cyt,ICC,IHC-P or IP
Mouse, Rat, Human
Synthetic peptide within Human Nogo B receptor. The exact sequence is proprietary.
A549, HUVEC and HeLa cell lysates.
This antibody was developed as part of a collaboration between Epitomics, the National Institutes of Health and the lab of Qing (Robert) Miao from the Medical College of Wisconsin.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.
This product is a recombinant rabbit monoclonal antibody.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery.
Protein modification; protein glycosylation.
Belongs to the UPP synthase family.
Endoplasmic reticulum membrane. Colocalizes with Nogo-B during VEGF and wound healing angiogenesis.
Zhao B et al. Comprehensive proteome quantification reveals NgBR as a new regulator for epithelial-mesenchymal transition of breast tumor cells. J Proteomics112C:38-52 (2014).
Read more (PubMed: 25173099) »