Overview

  • Product nameAnti-NOLC1 antibody
    See all NOLC1 primary antibodies
  • Description
    Rabbit polyclonal to NOLC1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within N terminal amino acids 1-50 of Human NOLC1 (NP_004732.2)

  • Positive control
    • Human colon carcinoma (FFPE section).

Properties

Applications

Our Abpromise guarantee covers the use of ab113217 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

Target

  • FunctionRelated to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.
  • Sequence similaritiesContains 1 LisH domain.
  • Post-translational
    modifications
    Undergoes rapid and massive phosphorylation/dephosphorylation cycles on CK2 and PKC sites. There is evidence suggesting that CDK1 kinase phosphorylates p130 at the M-phase.
  • Cellular localizationNucleus > nucleolus. Cytoplasm. Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase.
  • Information by UniProt
  • Database links
  • Alternative names
    • 140 kDa nucleolar phosphoprotein antibody
    • HCV NS5A trans regulated protein 13 antibody
    • HCV NS5A transactivated protein 13 antibody
    • HCV NS5A-transactivated protein 13 antibody
    • Hepatitis C virus NS5A transactivated protein 13 antibody
    • Hepatitis C virus NS5A-transactivated protein 13 antibody
    • KIAA0035 antibody
    • NOLC 1 antibody
    • NOLC1 antibody
    • NOLC1_HUMAN antibody
    • NOPP 130 antibody
    • NOPP 140 antibody
    • NOPP130 antibody
    • Nopp140 antibody
    • NS5ATP13 antibody
    • Nucleolar 130 kDa protein antibody
    • Nucleolar and coiled body phosphoprotein 1 antibody
    • Nucleolar and coiled body phosphprotein 1 antibody
    • Nucleolar and coiled-body phosphoprotein 1 antibody
    • Nucleolar phosphoprotein p130 antibody
    • Nucleolar protein p130 antibody
    • P130 antibody
    see all

Anti-NOLC1 antibody images

  • ab113217 at a 1/250 dilution staining NOLC1 in Human colon carcinoma by immunohistochemistry (FFPE section).

References for Anti-NOLC1 antibody (ab113217)

ab113217 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"