Nω-Propyl-L-arginine hydrochloride (ab146124)

Overview

  • Product name
    Nω-Propyl-L-arginine hydrochloride
  • Description
    Selective, reversible neuronal nitric oxide synthase (nNOS) inhibitor
  • Biological description
    Selective, reversible neuronal nitric oxide synthase (nNOS) inhibitor. Active in vivo. Nω-Propyl-L-arginine (ab146405) analog.
  • Purity
    > 98%

Properties

  • Chemical name
    N5-[Imino(propylamino)methyl]-L-ornithine hydrochloride
  • Molecular weight
    252.74
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C9H20N4O2.HCl
  • CAS Number
    137361-05-8
  • Storage instructions
    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    Cl.N[C@@H](CCCNC(=N)NCCC)C(=O)O
  • Source

    Synthetic

References

This product has been referenced in:
  • Gowda C  et al. The effects of N(omega)-propyl-L-arginine on reperfusion injury of skeletal muscle. Nitric Oxide 11:17-24 (2004). Read more (PubMed: 15350553) »
  • Klamer D  et al. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol 503:103-7 (2004). Read more (PubMed: 15496304) »
  • Cooper GR  et al. Cellular and enzymatic studies of N(omega)-propyl-l-arginine and S-ethyl-N-[4-(trifluoromethyl)phenyl]isothiourea as reversible, slowly dissociating inhibitors selective for the neuronal nitric oxide synthase isoform. Arch Biochem Biophys 375:183-94 (2000). Read more (PubMed: 10683266) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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