• Product nameAnti-NOP10 antibody
    See all NOP10 primary antibodies
  • Description
    Rabbit polyclonal to NOP10
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 1-50 (MFLQYYLNEQ GDRVYTLKKF DPMGQQTCSA HPARFSPDDK YSRHRITIKK) of Human NOLA3 (NP_061118).

  • Positive control
    • Jurkat cell lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab99084 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 8 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionRequired for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
  • Involvement in diseaseDefects in NOP10 are a cause of dyskeratosis congenita autosomal recessive (ARDKC) [MIM:224230]. ARDKC is a rare, progressive bone marrow failure syndrome characterized by the triad of reticulated skin hyperpigmentation, nail dystrophy, and mucosal leukoplakia. Early mortality is often associated with bone marrow failure, infections, fatal pulmonary complications, or malignancy.
  • Sequence similaritiesBelongs to the NOP10 family.
  • Cellular localizationNucleus > nucleolus. Nucleus > Cajal body. Also localized to Cajal bodies.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKCB1 antibody
    • H/ACA ribonucleoprotein complex subunit 3 antibody
    • homolog of yeast Nop10p antibody
    • MGC70651 antibody
    • NOLA3 antibody
    • NOP10 antibody
    • NOP10 ribonucleoprotein homolog (yeast) antibody
    • NOP10_HUMAN antibody
    • NOP10P antibody
    • Nucleolar protein 10 antibody
    • Nucleolar protein family A member 3 antibody
    • nucleolar protein family A, member 3 (H/ACA small nucleolar RNPs) antibody
    • snoRNP protein NOP10 antibody
    see all

Anti-NOP10 antibody images

  • Anti-NOP10 antibody (ab99084) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 8 kDa

References for Anti-NOP10 antibody (ab99084)

ab99084 has not yet been referenced specifically in any publications.

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