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Product Name
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Noradrenaline antibody
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See all Noradrenaline antibodies (3)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Noradrenaline
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Immunogen
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Chemical / Small Molecule by a Glutaraldehyde linker.
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Specificity
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Using catecholamine-Glutaraldehyde-BSA conjugates, antibody specificity was performed with an ELISA test by competition experiments, as follows:
(a) unconjugated or conjugated catecholamine concentration at half displacement
(b) Non-reduced conjugate
| Compound | Cross-reactivity ratio (a) | |
| Noradrenaline | 1 | | Octopamine | 1/31 | | Dopamine | 1/70 | | Adrenaline | 1/177 | | Noradrenaline (b) | 1/316 | | L-DOPA, Tyramine, unconjugated Noradrenaline | 1/>5000 |
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Tested applications
(see key)
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ELISA, IHC-Fr
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Immunohistochemistry: 1/2000 - 1/5000. Tested using a PAP techique on free floating rat locus coeruleus.
ELISA: assay dependent.
Not tested in other applications.
Optimal dilutions / concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Signal Transduction >> Growth Factors/Hormones >> Adrenalin
Neuroscience >> Neurotransmitter >> Biogenic Amines >> Noradrenaline
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Relevance
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Noradrenaline (NA) is a catecholamine neurotransmitter at postganglionic sympathetic fibres, produced following a series of steps from the essential amino acid phenylalanine. Terminal postganglionic sympathetic fibres have varicosities (where NA is synthesised and stored) which form synapses with the effector organ. The adrenal medulla is a major source of catecholamines (such as NA and adrenaline), however, most of the NA produced in the adrenal medulla is converted into adrenaline. NA is key in the fight-or-flight response and also directly increases heart rate, energy release from fat, and muscle readiness.
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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n/a
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Noradrenaline antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Noradrenaline
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Noradrenaline antibody - more information
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Protocols for Noradrenaline antibody |
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