Anti-Noradrenaline transporter antibody (ab78190)

Overview

  • Product name
    Anti-Noradrenaline transporter antibody
    See all Noradrenaline transporter primary antibodies
  • Description
    Rabbit polyclonal to Noradrenaline transporter
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog, Rhesus monkey
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 550 to the C-terminus of Human Noradrenaline transporter.

    (Peptide available as ab87371.)

  • Positive control
    • This antibody gave a positive signal in Human Brain and Spinal Cord Tissue Lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab78190 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 69 kDa (predicted molecular weight: 69 kDa).

Target

  • Function
    Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.
  • Involvement in disease
    Orthostatic intolerance
  • Sequence similarities
    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • NAT1 antibody
    • NET antibody
    • NET1 antibody
    • Neurotransmitter transporter antibody
    • Norepinephrine transporter antibody
    • SC6A2_HUMAN antibody
    • Slc6a2 antibody
    • SLC6A5 antibody
    • Sodium dependent noradrenaline transporter antibody
    • Sodium-dependent noradrenaline transporter antibody
    • Solute carrier family 6 (neurotransmitter transporter norepinephrine) member 5 antibody
    • Solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 antibody
    • Solute carrier family 6 member 2 antibody
    • Solute carrier family 6 member 5 antibody
    see all

Images

  • All lanes : Anti-Noradrenaline transporter antibody (ab78190) at 1 µg/ml

    Lane 1 : Human brain tissue lysate - total protein (ab29466)
    Lane 2 : Human spinal cord tissue lysate - total protein (ab29188)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) (ab65484) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 69 kDa
    Observed band size : 69 kDa
  • All lanes : Anti-Noradrenaline transporter antibody (ab78190) at 1 µg/ml

    Lane 1 : Brain (Mouse) Tissue Lysate
    Lane 2 : Brain (Rat) Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 69 kDa
    Observed band size : 69 kDa
    Additional bands at : 100 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 2 minutes

References

ab78190 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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