Anti-Norovirus antibody [B113M] (ab64042)

Overview

  • Product name
    Anti-Norovirus antibody [B113M]
  • Description
    Mouse monoclonal [B113M] to Norovirus
  • Specificity
    ab64042 recognizes the capsid protein of Norovirus (native and recombinant).
  • Tested applications
    Suitable for: ELISAmore details
  • Species reactivity
    Reacts with Norovirus. Does not react with Rotavirus, Adenovirus or Astrovirus.
  • Immunogen

    Purified native Norovirus, strain 8FIIa

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: 0.01M PBS, pH 7.2
  • Concentration information loading...
  • Purity
    Protein A purified
  • Purification notes
    ab64042 is >90% pure.
  • Clonality
    Monoclonal
  • Clone number
    B113M
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab64042 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.

Target

  • Relevance
    Norovirus is an RNA virus of the Caliciviridae taxonomic family, causes approximately 90% of epidemic non bacterial outbreaks of gastroenteritis around the world and is responsible for 50% of all foodborne outbreaks of gastroenteritis in the US. Norovirus affects people of all ages. The viruses are transmitted by faecally contaminated food or water and by person to person contact. Noroviruses can genetically be classified into 5 different genogroups (GI, GII, GIII, GIV, and GV) which can be further divided into different genetic clusters or genotypes. For example genogroup II, the most prevalent human genogroup, presently contains 19 genotypes. Genogroups I, II and IV infect humans, whereas genogroup III infects bovine species and genogroup V has recently been isolated in mice. Noroviruses contain a positive-sense RNA genome of approximately 7.5 kbp, encoding a major structural protein (VP1) of about 58~60 kDa and a minor capsid protein (VP2). The virus particles demonstrate an amorphous surface structure when visualized using electron microscopy and are between 27-38 nm in size.

References for Anti-Norovirus antibody [B113M] (ab64042)

ab64042 has not yet been referenced specifically in any publications.

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The antibodies have only been tested in ELISA. We do not have any data for western blotting.

Several of these are monoclonal antibodies that are raised against various strains of Norovirus, and the epi...

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Thank you for your enquiry. This product recognizes genotype I (Norwalk virus). It does not crossreact with genotype II (Hawaii virus). Unfortunately we do not have a published reference available for this clone.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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