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ab13654 has been referenced in 36 publications.

  • Yokoyama T  et al. Apoptosis is augmented in high-grade serous ovarian cancer by the combined inhibition of Bcl-2/Bcl-xL and PARP. Int J Oncol N/A:N/A (2017). WB ; Human . PubMed: 28350129
  • Inoue-Yamauchi A  et al. Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy. Nat Commun 8:16078 (2017). PubMed: 28714472
  • Hall JR  et al. Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes. Cell Death Dis 6:e1700 (2015). PubMed: 25789975
  • Yuan D  et al. Anti-angiogenic efficacy of 5'-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs. Oncotarget 6:29664-74 (2015). WB . PubMed: 26336994
  • Leverson JD  et al. Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax). Cell Death Dis 6:e1590 (2015). Human . PubMed: 25590800
  • Nalluri S  et al. EGFR signaling defines Mcl?1 survival dependency in neuroblastoma. Cancer Biol Ther 16:276-86 (2015). PubMed: 25756510
  • Moncunill-Massaguer C  et al. A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation. Oncotarget 6:41750-65 (2015). WB . PubMed: 26497683
  • Yang N  et al. Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound. PLoS One 10:e0125381 (2015). WB ; Human . PubMed: 25927702
  • Frik M  et al. In vitro and in vivo evaluation of water-soluble iminophosphorane ruthenium(II) compounds. A potential chemotherapeutic agent for triple negative breast cancer. J Med Chem 57:9995-10012 (2014). WB ; Human . PubMed: 25409416
  • Niewerth D  et al. Interferon-?-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines. J Hematol Oncol 7:7 (2014). WB ; Human . PubMed: 24418325
  • Abraham J  et al. Lineage of origin in rhabdomyosarcoma informs pharmacological response. Genes Dev 28:1578-91 (2014). WB ; Mouse . PubMed: 25030697
  • Geserick P  et al. The ratio of Mcl-1 and Noxa determines ABT737 resistance in squamous cell carcinoma of the skin. Cell Death Dis 5:e1412 (2014). Human . PubMed: 25210795
  • Sachweh MC  et al. Incompatible effects of p53 and HDAC inhibition on p21 expression and cell cycle progression. Cell Death Dis 4:e533 (2013). WB ; Human . PubMed: 23470540
  • Liu X  et al. Small molecule induced reactivation of mutant p53 in cancer cells. Nucleic Acids Res 41:6034-44 (2013). WB . PubMed: 23630318
  • Verfaillie T  et al. Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim. Biochem Biophys Res Commun 438:500-6 (2013). PubMed: 23916707
  • Matsushima-Miyagi T  et al. TRAIL and Noxa Are Selectively Upregulated in Prostate Cancer Cells Downstream of the RIG-I/MAVS Signaling Pathway by Nonreplicating Sendai Virus Particles. Clin Cancer Res 18:6271-83 (2012). PubMed: 23014529
  • Knowlton JJ  et al. Apoptosis induced by mammalian reovirus is beta interferon (IFN) independent and enhanced by IFN regulatory factor 3- and NF-?B-dependent expression of Noxa. J Virol 86:1650-60 (2012). PubMed: 22090144
  • Kerr E  et al. Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis. Cell Death Differ 19:1317-27 (2012). PubMed: 22322857
  • Yoshihara Y  et al. Inhibitory role of E2F-1 in the regulation of tumor suppressor p53 during DNA damage response. Biochem Biophys Res Commun 421:57-63 (2012). PubMed: 22480684
  • Sun R  et al. Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and mitochondria by up-regulating the transactivating p63 isoform alpha (TAP63alpha). J Biol Chem 286:15918-28 (2011). PubMed: 21367858
  • Morales AA  et al. Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 in Mcl-1-expressing myeloma cells. Blood 118:1329-39 (2011). PubMed: 21659544
  • Endo S  et al. Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells. Cancer Sci 102:605-13 (2011). WB ; Human . PubMed: 21205074
  • Saha MN  et al. RITA inhibits multiple myeloma cell growth through induction of p53-mediated caspase-dependent apoptosis and synergistically enhances nutlin-induced cytotoxic responses. Mol Cancer Ther 9:3041-51 (2010). WB ; Mouse . PubMed: 21062913
  • Samudio I  et al. Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction. J Clin Invest 120:142-56 (2010). WB ; Human . PubMed: 20038799
  • Wilhelm E  et al. TAF6delta orchestrates an apoptotic transcriptome profile and interacts functionally with p53. BMC Mol Biol 11:10 (2010). WB ; Human . PubMed: 20096117
  • Kim J  et al. PS-341 and histone deacetylase inhibitor synergistically induce apoptosis in head and neck squamous cell carcinoma cells. Mol Cancer Ther 9:1977-84 (2010). WB ; Human . PubMed: 20571067
  • Lim LY  et al. Mutant p53 mediates survival of breast cancer cells. Br J Cancer 101:1606-12 (2009). WB ; Human . PubMed: 19773755
  • Meurette O  et al. Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells. Cancer Res 69:5015-22 (2009). WB ; Human . PubMed: 19491273
  • Morales AA  et al. Reactive oxygen species are not required for an arsenic trioxide-induced antioxidant response or apoptosis. J Biol Chem 284:12886-95 (2009). WB ; Human . PubMed: 19279006
  • Naderi EH  et al. Activation of cAMP signaling inhibits DNA damage-induced apoptosis in BCP-ALL cells through abrogation of p53 accumulation. Blood 114:608-18 (2009). WB ; Human . PubMed: 19451550
  • Ploner C  et al. Repression of the BH3-only molecule PMAIP1/Noxa impairs glucocorticoid sensitivity of acute lymphoblastic leukemia cells. Apoptosis 14:821-8 (2009). WB ; Human . PubMed: 19421859
  • Matulis SM  et al. Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line. Mol Cancer Ther 8:1197-206 (2009). PubMed: 19417148
  • Bai Y  et al. Interferon-gamma induces XIAP-associated factor-1 and NOXA expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation. J Biol Chem : (2008). WB ; Human . PubMed: 18192275
  • Morales AA  et al. BH3-only proteins Noxa, Bmf and Bim are necessary for arsenic trioxide induced cell death in myeloma. Blood : (2008). PubMed: 18354037
  • Leong CO  et al. The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers. J Clin Invest 117:1370-80 (2007). PubMed: 17446929
  • Fribley AM  et al. Proteasome inhibitor PS-341 induces apoptosis in cisplatin-resistant squamous cell carcinoma cells by induction of Noxa. J Biol Chem 281:31440-7 (2006). PubMed: 16928686


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