Overview

  • Product nameAnti-NOXA1 antibody
    See all NOXA1 primary antibodies
  • Description
    Rabbit polyclonal to NOXA1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide corresponding to a region between amino acids 454-483 from the C terminal region of Human NOXA1.

  • Positive control
    • MDA-MB435 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab103007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 51 kDa.

Target

  • FunctionFunctions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3.
  • Tissue specificityWidely expressed. Detected in pancreas, liver, kidney, spleen, prostate, small intestine and colon.
  • Sequence similaritiesBelongs to the NCF2/NOXA1 family.
    Contains 1 OPR domain.
    Contains 1 SH3 domain.
    Contains 4 TPR repeats.
  • Developmental stageExpressed in fetal kidney.
  • DomainThe SH3 domain mediates interaction with NOXO1 and NCF1 and has autoregulatory function.
    The TPR repeats mediate interaction with RAC1.
  • Post-translational
    modifications
    Interaction with YWHAZ depends on phosphorylation by PKA.
  • Cellular localizationCytoplasm. Cell membrane. Translocation to membranes depends on NOXO1 or NCF1 and maybe RAC1.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen NY CO 31 antibody
    • Antigen NY-CO-31 antibody
    • FLJ25475 antibody
    • Inhibitory NADPH oxidase activator 1 antibody
    • MGC131800 antibody
    • NADPH oxidase activator 1 antibody
    • NCF2 like protein antibody
    • NCF2-like protein antibody
    • NOX activator 1 antibody
    • NOXA 1 antibody
    • Noxa1 antibody
    • NOXA1_HUMAN antibody
    • NY CO 31 antibody
    • p51 nox antibody
    • p51-nox antibody
    • p51NOX antibody
    • P67phox like factor antibody
    • P67phox-like factor antibody
    • SDCCAG31 antibody
    • Serologically defined colon cancer antigen 31 antibody
    see all

Anti-NOXA1 antibody images

  • Anti-NOXA1 antibody (ab103007) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg

    Predicted band size : 51 kDa

References for Anti-NOXA1 antibody (ab103007)

ab103007 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab103007.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"