Anti-Npas4 antibody (ab76758)
Key features and details
- Rabbit polyclonal to Npas4
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-Npas4 antibody
See all Npas4 primary antibodies -
Description
Rabbit polyclonal to Npas4 -
Host species
Rabbit -
Specificity
Antiserum reacts specifically with 87 kDa protein -
Tested applications
Suitable for: WBmore details
Unsuitable for: IHC-Fr -
Species reactivity
Reacts with: Mouse -
Immunogen
Synthetic peptide derived from C terminal domain of mouse Npas4 protein
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab76758 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use at an assay dependent concentration.
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Notes |
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WB
Use at an assay dependent concentration. |
Target
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Function
Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene. -
Tissue specificity
Brain. -
Sequence similarities
Contains 1 basic helix-loop-helix (bHLH) domain.
Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 2 PAS (PER-ARNT-SIM) domains. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 225872 Mouse
- SwissProt: Q8BGD7 Mouse
- Unigene: 287867 Mouse
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Alternative names
- bHLH PAS type transcription factor NXF antibody
- bHLHe79 antibody
- Class E basic helix-loop-helix protein 79 antibody
see all
Datasheets and documents
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Datasheet download
References (2)
ab76758 has been referenced in 2 publications.
- Xiong H et al. Circular RNA circ_0003420 mediates inflammation in sepsis-induced liver damage by downregulating neuronal PAS domain protein 4. Immunopharmacol Immunotoxicol 43:271-282 (2021). PubMed: 33719821
- Sribudiani Y et al. Variants in RET Associated With Hirschsprung's Disease Affect Binding of Transcription Factors and Gene Expression. Gastroenterology 140:572-582.e2 (2011). WB, IHC-Fr ; Mouse . PubMed: 20977903