Overview

  • Product name
    Anti-NPAT antibody [2648C6a]
    See all NPAT primary antibodies
  • Description
    Mouse monoclonal [2648C6a] to NPAT
  • Tested applications
    Suitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment (Human) from an internal sequence of NPAT.

  • Positive control
    • Recombinant human NPAT.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22 µm membrane.
  • Clonality
    Monoclonal
  • Clone number
    2648C6a
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab70595 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 240 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • Relevance
    NPAT is a 240kDa protein that associates with and can be phosphorylated by the CDK cyclin E–CDK2. The protein level of NPAT peaks at the G1/S boundary. Overexpression of NPAT accelerates S-phase entry suggesting that NPAT plays a role in S-phase entry.
  • Cellular localization
    Nuclear
  • Database links
  • Alternative names
    • E14 antibody
    • nuclear protein ataxia telangiectasia locus antibody
    • nuclear protein in the AT region antibody

Images

References

This product has been referenced in:
  • Mano M  et al. Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction. Proc Natl Acad Sci U S A 112:11276-81 (2015). Read more (PubMed: 26305933) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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