Overview

  • Product name
    Anti-NPEPPS antibody [2649C4a]
    See all NPEPPS primary antibodies
  • Description
    Mouse monoclonal [2649C4a] to NPEPPS
  • Tested applications
    Suitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment comprising of 50-200 amino acids from the internal region of human NPEPPS.

  • Positive control
    • Recombinant fragment of human NPEPPS.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, (8.0mM Sodium phosphate, 3.0mM Potassium chloride, 140mM Sodium chloride, 1.5mM Potassium phosphate), pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    ab76558 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
  • Clonality
    Monoclonal
  • Clone number
    2649C4a
  • Isotype
    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab76558 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 2 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 103 kDa).
Dot blot Use at an assay dependent dilution.

Target

  • Function
    Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain.
  • Tissue specificity
    Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level).
  • Sequence similarities
    Belongs to the peptidase M1 family.
  • Cellular localization
    Cytoplasm > cytosol. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AAP-S antibody
    • Aminopeptidase puromycin sensitive antibody
    • Cytosol alanyl aminopeptidase antibody
    • Metalloprotease 100 antibody
    • Metalloprotease MP100 antibody
    • MP 100 antibody
    • MP100 antibody
    • Npepps antibody
    • Psa antibody
    • PSA_HUMAN antibody
    • Puromycin sensitive aminopeptidase antibody
    • Puromycin-sensitive aminopeptidase antibody
    see all

Images

References

ab76558 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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