Overview

  • Product nameAnti-NPR2L antibody
    See all NPR2L primary antibodies
  • Description
    Rabbit polyclonal to NPR2L
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide from a region within GSGCRIECIF FSEFHPTLGP KITYQVPEDF ISRELFDTVQ VYIITKPELQ, corresponding to N terminal amino acids 2-51 of Human NPR2L (NP_006536).

  • Positive control
    • OVCAR-3 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab89722 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionSuppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.
  • Tissue specificityMost abundant in skeletal muscle, followed by brain, liver and pancreas, with lower amounts in lung, kidney, placenta and heart. Expressed in most lung cancer cell lines tested.
  • Sequence similaritiesBelongs to the NPR2 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2810446G01Rik antibody
    • G21 protein antibody
    • Gene 21 protein antibody
    • Homologous to yeast nitrogen permease (candidate tumor suppressor) antibody
    • Homologous to yeast nitrogen permease antibody
    • Nitrogen permease regulator 2-like protein antibody
    • Nitrogen permease regulator-like 2 (S. cerevisiae) antibody
    • NPR 2L antibody
    • NPR L2 antibody
    • NPR like 2 antibody
    • NPR2 antibody
    • NPR2 like antibody
    • NPR2-like protein antibody
    • NPR2L antibody
    • NPRL 2 antibody
    • NPRL2 antibody
    • NPRL2_HUMAN antibody
    • Tumor suppressor candidate 4 antibody
    • TUSC 4 antibody
    • TUSC 4 protein antibody
    • TUSC4 antibody
    • TUSC4 protein antibody
    see all

Anti-NPR2L antibody images

  • Anti-NPR2L antibody (ab89722) at 1 µg/ml (in 5% skim milk / PBS buffer) + OVCAR-3 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 44 kDa
    Observed band size : 44 kDa

References for Anti-NPR2L antibody (ab89722)

ab89722 has not yet been referenced specifically in any publications.

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