Overview

  • Product nameAnti-NPVF antibody
  • Description
    Rabbit polyclonal to NPVF
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: TANLPLRSGR NMEVSLVRRV PNLPQRFGRT TTAKSVCRML SDLCQGSMHS PCANDLFYSM TCQHQEIQNP DQ, corresponding to amino acids 105-176 of Human NPVF.

  • Positive control
    • RT4, U-251 MG, Human Liver and Human Tonsil lysates, Human kidney tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab122738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250 - 1/500.
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionNeuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine-induced analgesia.
  • Tissue specificityIsoform 1 is specifically expressed in the retina. Neuropeptides RFRP-1 and NPVF are detected in the hypothalamus.
  • Sequence similaritiesBelongs to the FARP (FMRFamide related peptide) family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C7orf9 antibody
    • Neuropeptide NPSF antibody
    • Neuropeptide NPVF antibody
    • Neuropeptide RFRP-1 antibody
    • Neuropeptide RFRP-2 antibody
    • Neuropeptide RFRP-3 antibody
    • Neuropeptide VF antibody
    • NPVF antibody
    • RFRP antibody
    • RFRP_HUMAN antibody
    see all

Anti-NPVF antibody images

  • All lanes : Anti-NPVF antibody (ab122738) at 1/250 dilution

    Lane 1 : RT4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate
  • ab122738 at 1/200 dilution staining NPVF in Paraffin-embedded Human kidney tissue by Immunohistochemistry.

References for Anti-NPVF antibody (ab122738)

ab122738 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"