Overview

  • Product name
  • Description
    Goat polyclonal to NPY2R
  • Tested applications
    Suitable for: WB, ELISA, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Dog, Chimpanzee, Rhesus monkey
  • Immunogen

    Synthetic peptide:

    KAKKNLEVKKNN

    by a Cysteine residue linker, corresponding to amino acids 362-373 of Mouse NPY2R

  • Positive control
    • Mouse Brain and Rat Brain lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab59137 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 40, 45 kDa (predicted molecular weight: 42 kDa).
ELISA 1/32000.
IP Use at an assay dependent dilution.

Target

  • Function
    Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
  • Tissue specificity
    High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Neuropeptide Y receptor type 2 antibody
    • Neuropeptide Y receptor Y2 antibody
    • NPY-Y2 receptor antibody
    • NPY2-R antibody
    • NPY2R antibody
    • NPY2R_HUMAN antibody
    • Y2 receptor antibody
    see all

Images

  • Anti-NPY2R antibody (ab59137) at 0.1 µg/ml + Rat brain lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 42 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.

References

ab59137 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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