Overview

  • Product name
  • Description
    Rabbit polyclonal to NR1D1
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 246-518 of Human NR1D1 (P20393).

  • Positive control
    • 293T, A431, Jurkat and Raji whole cell lysates; A431 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab126271 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 67 kDa.
ICC/IF 1/100 - 1/500. Paraformaldehyde-fixed.

Target

  • Function
    Functions as a constitutive transcriptional repressor. Possible receptor for triiodothyronine.
  • Tissue specificity
    Expressed in all tissues and cell lines examined. Expressed at high levels in some squamous carcinoma cell lines.
  • Sequence similarities
    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Domain
    Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • EAR-1 antibody
    • EAR1 antibody
    • ERBA-related 1 antibody
    • hRev antibody
    • Nr1d1 antibody
    • NR1D1_HUMAN antibody
    • Nuclear receptor Rev ErbA alpha antibody
    • Nuclear receptor subfamily 1 group D member 1 antibody
    • Rev erbAalpha antibody
    • Rev erbalpha antibody
    • Rev-erbA-alpha antibody
    • Rev-ErbAalpha antibody
    • Reverba antibody
    • THRA1 antibody
    • THRAL antibody
    • Thyroid hormone receptor, alpha like antibody
    • Thyroid hormone receptor, alpha-1- like antibody
    • V-erbA-related protein 1 antibody
    see all

Images

  • Anti-NR1D1 antibody (ab126271) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

    Predicted band size : 67 kDa
  • ab126271, at 1/500 dilution, staining NR1D1 in paraformaldehyde-fixed A431 cells by Immunofluorescence. The lower image is co-stained with Hoechst 33342.

References

ab126271 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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