Anti-NR2E1 / Tailless antibody [EPR4491] (ab109179)

Overview

  • Product nameAnti-NR2E1 / Tailless antibody [EPR4491]
    See all NR2E1 / Tailless primary antibodies
  • Description
    Rabbit monoclonal [EPR4491] to NR2E1 / Tailless
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human NR2E1/Tailless (UniProt Q9Y466).

  • Positive control
    • Fetal brain, Human hippocampus, SH-SY5Y and Jurkat lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Properties

Applications

Our Abpromise guarantee covers the use of ab109179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 43 kDa.
  • Application notesIs unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • FunctionOrphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development.
    • Tissue specificityBrain specific. Present in all brain sections tested, highest levels in the caudate nucleus and hippocampus, weakest levels in the thalamus.
    • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR2 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • hTll antibody
      • nr2e1 antibody
      • NR2E1_HUMAN antibody
      • Nuclear receptor subfamily 2 group E member 1 antibody
      • Nuclear receptor TLX antibody
      • Orphan nuclear receptor NR2E1 antibody
      • Protein tailless homolog antibody
      • Tailless homolog antibody
      • Tll antibody
      • TLX antibody
      • XTLL antibody
      see all

    Anti-NR2E1 / Tailless antibody [EPR4491] images

    • All lanes : Anti-NR2E1 / Tailless antibody [EPR4491] (ab109179) at 1/1000 dilution

      Lane 1 : Fetal brain lysate
      Lane 2 : Human hippocampus lysate
      Lane 3 : SH-SY5Y lysate
      Lane 4 : Jurkat lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 43 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References for Anti-NR2E1 / Tailless antibody [EPR4491] (ab109179)

    ab109179 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"