Overview

  • Product name
  • Description
    Goat polyclonal to NR3B
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    C-EAPPHSGRPGSQ

    , corresponding to C terminal amino acids 1031-1042 of Human NR3B (NP_619635.1).

  • Positive control
    • Human Brain (Cerebellum and Cerebral Cortex) lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab106808 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106808 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 113 kDa).

Target

  • Function
    NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.
  • Sequence similarities
    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3B/GRIN3B subfamily.
  • Cellular localization
    Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Requires the presence of GRIN1 to be targeted at the plasma membrane.
  • Information by UniProt
  • Database links
  • Form
    A subunit of the N-methyl-D-aspartate (NMDA) receptor, which belongs to the superfamily of glutamate-regulated ion channels that are present in neurons throughout the central nervous system.
  • Alternative names
    • GluN3B antibody
    • Glutamate [NMDA] receptor subunit 3B antibody
    • Glutamate receptor ionotropic N methyl D aspartate 3B antibody
    • Glutamate receptor ionotropic NMDA 3B antibody
    • GRIN3B antibody
    • N-methyl-D-aspartate receptor subtype 3B antibody
    • NMD3B_HUMAN antibody
    • NMDA receptor subunit 3B antibody
    • NMDA type glutamate receptor subunit NR3B antibody
    • NMDAR3B antibody
    • NR3B antibody
    see all

Images

  • Anti-NR3B antibody (ab106808) at 0.5 µg/ml + Human cerebellum lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 113 kDa

References

ab106808 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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