Overview

  • Product name
    Anti-NR3B antibody - C-terminal
    See all NR3B primary antibodies
  • Description
    Rabbit polyclonal to NR3B - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human NR3B aa 903-933 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: O60391

  • Positive control
    • A549 cell lysate; Human brain tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab170661 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 112 kDa.
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.
  • Sequence similarities
    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3B/GRIN3B subfamily.
  • Cellular localization
    Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Requires the presence of GRIN1 to be targeted at the plasma membrane.
  • Information by UniProt
  • Database links
  • Form
    A subunit of the N-methyl-D-aspartate (NMDA) receptor, which belongs to the superfamily of glutamate-regulated ion channels that are present in neurons throughout the central nervous system.
  • Alternative names
    • GluN3B antibody
    • Glutamate [NMDA] receptor subunit 3B antibody
    • Glutamate receptor ionotropic N methyl D aspartate 3B antibody
    • Glutamate receptor ionotropic NMDA 3B antibody
    • GRIN3B antibody
    • N-methyl-D-aspartate receptor subtype 3B antibody
    • NMD3B_HUMAN antibody
    • NMDA receptor subunit 3B antibody
    • NMDA type glutamate receptor subunit NR3B antibody
    • NMDAR3B antibody
    • NR3B antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue labeling NR3B with ab170661 at 1/10 dilution, followed by a peroxidase conjugated secondary antibody and DAB staining.

  • Anti-NR3B antibody - C-terminal (ab170661) at 1/100 dilution + A549 cell lysate at 35 µg

    Predicted band size: 112 kDa

References

ab170661 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab170661.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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