Anti-Nrf2 antibody [EP1808Y] (ab62352)

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ab62352 has been referenced in 41 publications.

  • Kerr F  et al. Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease. PLoS Genet 13:e1006593 (2017). ICC/IF ; Human . PubMed: 28253260
  • Arai A  et al. p62/SQSTM1 levels predicts radiotherapy resistance in hypopharyngeal carcinomas. Am J Cancer Res 7:881-891 (2017). WB ; Human . PubMed: 28469960
  • Tian Y  et al. Modification of platinum sensitivity by KEAP1/NRF2 signals in non-small cell lung cancer. J Hematol Oncol 9:83 (2016). PubMed: 27601007
  • Spriggs S  et al. Effect of Repeated Daily Dosing with 2,4-Dinitrochlorobenzene on Glutathione Biosynthesis and Nrf2 Activation in Reconstructed Human Epidermis. Toxicol Sci 154:5-15 (2016). PubMed: 27492222
  • Latham Birt SH  et al. Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway. J Lipid Res 57:1204-18 (2016). PubMed: 27185859
  • Comerford SA  et al. Hepatoblastoma modeling in mice places Nrf2 within a cancer field established by mutant ß-catenin. JCI Insight 1:e88549 (2016). WB ; Human . PubMed: 27734029
  • Pan H  et al. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Cell Res 26:190-205 (2016). WB, ChIP ; Human . PubMed: 26768768
  • Wu ST  et al. Cellular effects induced by 17-ß-estradiol to reduce the survival of renal cell carcinoma cells. J Biomed Sci 23:67 (2016). WB ; Human . PubMed: 27680214
  • Zhang C  et al. NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction. Oncotarget 7:73593-73606 (2016). ChIP ; Human . PubMed: 27713154
  • Schumacher FR  et al. RNAi Screen for NRF2 Inducers Identifies Targets That Rescue Primary Lung Epithelial Cells from Cigarette Smoke Induced Radical Stress. PLoS One 11:e0166352 (2016). WB ; Human . PubMed: 27832175
  • Gendron JM  et al. Using the Ubiquitin-modified Proteome to Monitor Distinct and Spatially Restricted Protein Homeostasis Dysfunction. Mol Cell Proteomics 15:2576-93 (2016). PubMed: 27185884
  • Lim R  et al. The transcription factor Nrf2 is decreased after spontaneous term labour in human fetal membranes where it exerts anti-inflammatory properties. Placenta 36:7-17 (2015). PubMed: 25468547
  • Olayanju A  et al. Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2. Free Radic Biol Med 78:202-12 (2015). WB, IRMA ; Mouse . PubMed: 25445704
  • DeNicola GM  et al. NRF2 regulates serine biosynthesis in non-small cell lung cancer. Nat Genet N/A:N/A (2015). WB ; Mouse . PubMed: 26482881
  • Anandhan A  et al. Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways. Neurobiol Dis 81:76-92 (2015). WB ; Rat . PubMed: 25497688
  • Orthwein A  et al. A mechanism for the suppression of homologous recombination in G1 cells. Nature 528:422-6 (2015). WB ; Human . PubMed: 26649820
  • Naik P  et al. Effect of full flavor and denicotinized cigarettes exposure on the brain microvascular endothelium: a microarray-based gene expression study using a human immortalized BBB endothelial cell line. BMC Neurosci 16:38 (2015). PubMed: 26099276
  • Fishel ML  et al. Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2. J Biol Chem 290:3057-68 (2015). WB ; Human . PubMed: 25492865
  • Kigoshi Y  et al. CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2. Sci Rep 5:12857 (2015). ICC/IF ; Human . PubMed: 26238671
  • An J  et al. Oligomeric proanthocyanidins alleviate hexabromocyclododecane-induced cytotoxicity in HepG2 cells through regulation on ROS formation and mitochondrial pathway. Toxicol In Vitro 28:319-26 (2014). Human . PubMed: 24291159
  • Tanaka K  et al. A novel acylaminoimidazole derivative, WN1316, alleviates disease progression via suppression of glial inflammation in ALS mouse model. PLoS One 9:e87728 (2014). WB ; Human . PubMed: 24498180
  • Stachel I  et al. Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stress response gene immediate early response-3 (IER3) in colonic epithelial cells: a novel mechanism of cellular adaption to inflammatory stress. J Biol Chem 289:1917-29 (2014). WB . PubMed: 24311782
  • Kwon SJ  et al. High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening. Nat Commun 5:3739 (2014). PubMed: 24799042
  • Havermann S  et al. Caffeic Acid Phenethylester Increases Stress Resistance and Enhances Lifespan in Caenorhabditis elegans by Modulation of the Insulin-Like DAF-16 Signalling Pathway. PLoS One 9:e100256 (2014). WB . PubMed: 24964141
  • Zhao C  et al. Nuclear Factor E2-related Factor-2 (Nrf2) Is Required for NLRP3 and AIM2 Inflammasome Activation. J Biol Chem 289:17020-17029 (2014). WB . PubMed: 24798340
  • Peng S  et al. In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids. Am J Physiol Gastrointest Liver Physiol 307:G129-39 (2014). WB ; Human . PubMed: 24852569
  • Zhang Y  et al. Coordinated regulation of protein synthesis and degradation by mTORC1. Nature N/A:N/A (2014). PubMed: 25043031
  • Dickinson SE  et al. The effect of sulforaphane on histone deacetylase activity in keratinocytes: Differences between in vitro and in vivo analyses. Mol Carcinog N/A:N/A (2014). PubMed: 25307283
  • Santacana M  et al. A 9-protein biomarker molecular signature for predicting histologic type in endometrial carcinoma by immunohistochemistry. Hum Pathol 45:2394-403 (2014). PubMed: 25282036
  • Hu T  et al. Clinicopathologic significance of CXCR4 and Nrf2 in colorectal cancer. J Biomed Res 27:283-90 (2013). IHC ; Human . PubMed: 23885267
  • Faronato M  et al. The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit. Cell Cycle 12:1964-77 (2013). Human . PubMed: 23708518
  • Ma J  et al. PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function. Mol Cell Biol 32:1506-17 (2012). WB . PubMed: 22331464
  • Scannevin RH  et al. Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway. J Pharmacol Exp Ther 341:274-84 (2012). PubMed: 22267202
  • Chorley BN  et al. Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha. Nucleic Acids Res 40:7416-29 (2012). ChIP, CHIPseq ; Human . PubMed: 22581777
  • Kim AD  et al. Increased glutathione synthesis following nrf2 activation by vanadyl sulfate in human chang liver cells. Int J Mol Sci 12:8878-94 (2011). ICC/IF ; Human . PubMed: 22272109
  • Elisia I  et al. Tryptophan from human milk induces oxidative stress and upregulates the Nrf-2-mediated stress response in human intestinal cell lines. J Nutr 141:1417-23 (2011). PubMed: 21677072
  • Jiang T  et al. High Levels of Nrf2 Determine Chemoresistance in Type II Endometrial Cancer. Cancer Res 70:5486-96 (2010). WB, IHC-P ; Human . PubMed: 20530669
  • Rao VA  et al. The antioxidant transcription factor nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone. J Biol Chem 285:34447-59 (2010). WB, ICC/IF ; Human . PubMed: 20805228
  • Rachakonda G  et al. Increased cell migration and plasticity in Nrf2-deficient cancer cell lines. Oncogene 29:3703-14 (2010). IP ; Human . PubMed: 20440267
  • Arlt A  et al. Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2). Oncogene 28:3983-96 (2009). IHC-Fr ; Human . PubMed: 19734940
  • Turpaev K & Drapier JC Stimulatory effect of benzylidenemalononitrile tyrphostins on expression of NO-dependent genes in U-937 monocytic cells. Eur J Pharmacol 606:1-8 (2009). PubMed: 19374863


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