Recombinant extracellular domain of rat NRG1 (Neuregulin 1) protein.
NRG1 (Neuregulin 1) binds to e-erbB3 and c-erbB4 receptors on mammary and neuronal cells with low and high affinity, respectively. NRG1 exists in several isoforms, which are classified in two groups, a and b, that differ in their EGF-like domain and in receptor binding affinity. This antibody detects pan-NRG1 and is not subtype specific.
Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause.
Our Abpromise guarantee covers the use of ab2369 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. ABC method.|
|IHC-Fr||1/50 - 1/100. ABC method.|
ab2369 has not yet been referenced specifically in any publications.