Overview

  • Product nameAnti-NSDHL antibody
    See all NSDHL primary antibodies
  • Description
    Rabbit polyclonal to NSDHL
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant full length Human protein NSDHL (NP_057006.1)

  • Positive control
    • Mouse lung tissue, A431 cell line and NSDHL transfected 293T cell lysates

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab102805 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 42 kDa.

Target

  • Tissue specificityBrain, heart, liver, lung, kidney, skin and placenta.
  • PathwaySteroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 4/6.
  • Involvement in diseaseDefects in NSDHL are the cause of congenital hemidysplasia with ichthyosiform erythroderma and limb defects (CHILD) [MIM:308050]. CHILD is an X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, which typically results in male lethality. Clinically, it is characterized by congenital, unilateral, ichthyosisform erythroderma with striking lateralization, sharp midline demarcation, and ipsilateral limb defects and hypoplasia of the body. Limbs defects range from hypoplasia of digits or ribs to complete amelia, often including scoliosis.
    Defects in NSDHL are the cause of CK syndrome (CKS) [MIM:300831]. CKS is a disorder characterized by mild to severe cognitive impairment, seizures, microcephaly, cerebral cortical malformations, dysmorphic facial features, and thin body habitus.
  • Sequence similaritiesBelongs to the 3-beta-HSD family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • decarboxylating antibody
    • H105E3 antibody
    • H105e3 protein antibody
    • NAD(P) dependent steroid dehydrogenase like antibody
    • NSDHL antibody
    • NSDHL_HUMAN antibody
    • Protein H105e3 antibody
    • SDR31E1 antibody
    • Short chain dehydrogenase/reductase family 31E member 1 antibody
    • Sterol 4 alpha carboxylate 3 dehydrogenase decarboxylating antibody
    • Sterol-4-alpha-carboxylate 3-dehydrogenase antibody
    • XAP104 antibody
    see all

Anti-NSDHL antibody images

  • Anti-NSDHL antibody (ab102805) at 5 µg/ml + Mouse lung tissue lysate at 50 µg

    Secondary
    Goat anti-Mouse IgG HRP at 1/2500 dilution

    Predicted band size : 42 kDa
  • Anti-NSDHL antibody (ab102805) at 5 µg/ml + A431 cell lysate at 50 µg

    Predicted band size : 42 kDa
  • All lanes : Anti-NSDHL antibody (ab102805) at 5 µg/ml

    Lane 1 : NSDHL transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 42 kDa

References for Anti-NSDHL antibody (ab102805)

ab102805 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab102805.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"