Overview

  • Product nameAnti-NSDHL antibody
    See all NSDHL primary antibodies
  • Description
    Mouse polyclonal to NSDHL
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human NSDHL protein (NP_057006.1)

  • Positive control
    • Human liver tissue lysate, NSDHL transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab92904 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Predicted molecular weight: 42 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Tissue specificityBrain, heart, liver, lung, kidney, skin and placenta.
    • PathwaySteroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 4/6.
    • Involvement in diseaseDefects in NSDHL are the cause of congenital hemidysplasia with ichthyosiform erythroderma and limb defects (CHILD) [MIM:308050]. CHILD is an X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, which typically results in male lethality. Clinically, it is characterized by congenital, unilateral, ichthyosisform erythroderma with striking lateralization, sharp midline demarcation, and ipsilateral limb defects and hypoplasia of the body. Limbs defects range from hypoplasia of digits or ribs to complete amelia, often including scoliosis.
      Defects in NSDHL are the cause of CK syndrome (CKS) [MIM:300831]. CKS is a disorder characterized by mild to severe cognitive impairment, seizures, microcephaly, cerebral cortical malformations, dysmorphic facial features, and thin body habitus.
    • Sequence similaritiesBelongs to the 3-beta-HSD family.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • decarboxylating antibody
      • H105E3 antibody
      • H105e3 protein antibody
      • NAD(P) dependent steroid dehydrogenase like antibody
      • NSDHL antibody
      • NSDHL_HUMAN antibody
      • Protein H105e3 antibody
      • SDR31E1 antibody
      • Short chain dehydrogenase/reductase family 31E member 1 antibody
      • Sterol 4 alpha carboxylate 3 dehydrogenase decarboxylating antibody
      • Sterol-4-alpha-carboxylate 3-dehydrogenase antibody
      • XAP104 antibody
      see all

    Anti-NSDHL antibody images

    • Anti-NSDHL antibody (ab92904) at 1/500 dilution + Human liver tissue lysate at 50 µg

      Predicted band size : 42 kDa
    • All lanes : Anti-NSDHL antibody (ab92904) at 1/500 dilution

      Lane 1 : NSDHL transfected 293T cell lysate
      Lane 2 : Untransfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.


      Predicted band size : 42 kDa

    References for Anti-NSDHL antibody (ab92904)

    ab92904 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92904.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"