Overview

  • Product name
  • Description
    Rabbit polyclonal to NSE
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).

  • Positive control
    • IMR cells. Pancreas.

Properties

Applications

Our Abpromise guarantee covers the use of ab15486 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/300 for 10 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0 for 10 minutes, followed by cooling at RT for 20 minutes.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
    • Tissue specificity
      The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
    • Pathway
      Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
    • Sequence similarities
      Belongs to the enolase family.
    • Developmental stage
      During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.
    • Cellular localization
      Cytoplasm. Cell membrane. Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.
    • Information by UniProt
    • Database links
    • Alternative names
      • 2 phospho D glycerate hydrolyase antibody
      • 2-phospho-D-glycerate hydro-lyase antibody
      • Eno 2 antibody
      • ENO2 antibody
      • ENOG antibody
      • ENOG_HUMAN antibody
      • Enolase 2 (gamma, neuronal) antibody
      • Enolase 2 antibody
      • Enolase 2 gamma neuronal antibody
      • Enolase2 antibody
      • Epididymis secretory protein Li 279 antibody
      • Gamma enolase antibody
      • Gamma-enolase antibody
      • HEL S 279 antibody
      • Neural enolase antibody
      • Neuron specific enolase antibody
      • Neuron specific gamma enolase antibody
      • Neuron-specific enolase antibody
      • neuronal enriched enolase antibody
      • Neurone specific enolase antibody
      • NSE antibody
      see all

    Images

    • ab15486 staining NSE in human pancreas by Immunohistochemistry (FFPE-sections).

    References

    ab15486 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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