Anti-NSE antibody - Neuronal Marker (ab16873)


  • Product nameAnti-NSE antibody - Neuronal Marker
    See all NSE primary antibodies
  • Description
    Rabbit polyclonal to NSE - Neuronal Marker
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Goat, Chicken, Macaque Monkey
  • Immunogen

    Recombinant full length protein (Human).

  • Positive control
    • U87MG whole cell lysate.



Our Abpromise guarantee covers the use of ab16873 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 47 kDa.


  • FunctionHas neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
  • Tissue specificityThe alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
  • PathwayCarbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
  • Sequence similaritiesBelongs to the enolase family.
  • Developmental stageDuring ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.
  • Cellular localizationCytoplasm. Cell membrane. Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2 phospho D glycerate hydrolyase antibody
    • 2-phospho-D-glycerate hydro-lyase antibody
    • Eno 2 antibody
    • ENO2 antibody
    • ENOG antibody
    • ENOG_HUMAN antibody
    • Enolase 2 (gamma, neuronal) antibody
    • Enolase 2 antibody
    • Enolase 2 gamma neuronal antibody
    • Enolase2 antibody
    • Epididymis secretory protein Li 279 antibody
    • Gamma enolase antibody
    • Gamma-enolase antibody
    • HEL S 279 antibody
    • Neural enolase antibody
    • Neuron specific enolase antibody
    • Neuron specific gamma enolase antibody
    • Neuron-specific enolase antibody
    • Neurone specific enolase antibody
    • NSE antibody
    see all

Anti-NSE antibody - Neuronal Marker images

  • Predicted band size : 47 kDa

    ab16873 at 1/2000 dilution staining NSE by Western blot.

    Lane 1: U87MG cell lysates.

    Lane 2: Mouse brain

    Lane 3: Rat brain.

References for Anti-NSE antibody - Neuronal Marker (ab16873)

This product has been referenced in:
  • Ray B  et al. Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research. Mol Brain 7:63 (2014). WB ; Human . Read more (PubMed: 25223359) »
  • Silverberg GD  et al. Amyloid deposition and influx transporter expression at the blood-brain barrier increase in normal aging. J Neuropathol Exp Neurol 69:98-108 (2010). WB ; Rat . Read more (PubMed: 20010299) »

See all 4 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Rat Tissue lysate - whole (brain)
Loading amount 10 µg
Specification brain
Gel Running Conditions Reduced Denaturing
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C


Verified customer

Submitted Jan 05 2010

Thank you for your enquiry. Unfortunately the antibody is not available separately as the Fab2 and Fc fragment. I hope this information helps, please do not hesitate to contact us if you need any more advice or information.