Anti-nSMase antibody - N-terminal (ab95061)

Overview

  • Product name
    Anti-nSMase antibody - N-terminal
    See all nSMase primary antibodies
  • Description
    Rabbit polyclonal to nSMase - N-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide selected from the N terminal region of Human nSMase (NP_003071) conjugated to KLH.

  • Positive control
    • Mouse lung tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab95061 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 47 kDa.

Target

  • Function
    Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
  • Sequence similarities
    Belongs to the neutral sphingomyelinase family.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ISC1 antibody
    • Lyso platelet activating factor phospholipase C antibody
    • Lyso-PAF-PLC antibody
    • Lyso-platelet-activating factor-phospholipase C antibody
    • N-SMase antibody
    • Neutral sphingomyelinase antibody
    • NSMA_HUMAN antibody
    • nSMase antibody
    • NSMASE1 antibody
    • Smpd2 antibody
    • Sphingomyelin phosphodiesterase 2 antibody
    • Sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) antibody
    see all

Images

  • Anti-nSMase antibody - N-terminal (ab95061) at 1/50 dilution (in TTBS/1% NFDM for 1 hr. at room temperature) + Mouse lung tissue lysate at 35 µg

    Secondary
    Enzyme-linked secondary antibody (typically horseradish peroxidase or alkaline phosphatase) in TTBS/1% NFDM for 30 min. at room temperature.

    Predicted band size : 47 kDa

References

ab95061 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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