Overview

  • Product nameAnti-NSUN2 antibody
    See all NSUN2 primary antibodies
  • Description
    Rabbit polyclonal to NSUN2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids 426-455 of Human NSUN2 (NP_060225.4).

  • Positive control
    • Mouse spleen tissue lysates

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab107262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 86 kDa.

Target

  • FunctionRNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Not able to modify tRNAs at positions 48 or 49. May act downstream of Myc to regulate epidermal cell growth and proliferation.
  • Sequence similaritiesBelongs to the methyltransferase superfamily. RsmB/NOP family. TRM4 subfamily.
  • Post-translational
    modifications
    Phosphorylated at Ser-139 by Aurora-B/STK12 during mitosis, leading to abolish methyltransferase activity and the interaction with NPM1.
  • Cellular localizationNucleus > nucleolus. Cytoplasm. Concentrated in the nucleolus during interphase and distributed in the perichromosome and cytoplasm during mitosis.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5 methycytoisine methyltransferase antibody
    • D13Wsu123e antibody
    • FLJ20303 antibody
    • hTrm4 antibody
    • MISU antibody
    • Myc induced SUN domain containing protein antibody
    • NOL1/NOP2/Sun domain family 2 antibody
    • NOL1/NOP2/Sun domain family 2 protein antibody
    • NOL1/NOP2/Sun domain family member 2 antibody
    • NSUN 2 antibody
    • NSUN2 antibody
    • NSUN2_HUMAN antibody
    • SAKI antibody
    • Substrate of AIM1/Aurora kinase B antibody
    • TRM4 antibody
    • tRNA (cytosine 5 ) methyltransferase antibody
    • tRNA (cytosine 5 ) methyltransferase NSUN2 antibody
    • tRNA (cytosine(34)-C(5))-methyltransferase antibody
    • tRNA (cytosine-5-)-methyltransferase antibody
    • tRNA methyltransferase 4 homolo antibody
    • tRNA methyltransferase 4 homolog antibody
    see all

Anti-NSUN2 antibody images

  • Anti-NSUN2 antibody (ab107262) at 1/100 dilution + Mouse spleen tissue lysates at 35 µg

    Predicted band size : 86 kDa

References for Anti-NSUN2 antibody (ab107262)

ab107262 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab107262.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"