Overview

  • Product nameAnti-NT5M antibody
  • Description
    Mouse monoclonal to NT5M
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: CTSPIKMFKY CPYEKYAWVE KYFGPDFLEQ IVLTRDKTVV SADLLIDDRP DITGAEPTPS WEHVLFTACH NQHLQLQPPR RRLHSWADDW KAILDSKRPC , corresponding to amino acids 129-228 of Human NT5M

Properties

Applications

Our Abpromise guarantee covers the use of ab57518 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionDephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
    • Tissue specificityHighly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas.
    • Sequence similaritiesBelongs to the 5'(3')-deoxyribonucleotidase family.
    • Cellular localizationMitochondrion.
    • Information by UniProt
    • Database links
    • Alternative names
      • 3''-nucleotidase antibody
      • 5'' antibody
      • 5''(3'')-deoxyribonucleotidase antibody
      • 5'(3')-deoxyribonucleotidase, mitochondrial antibody
      • 5',3'-nucleotidase, mitochondrial antibody
      • Deoxy-5''-nucleotidase 2 antibody
      • dNT-2 antibody
      • DNT2 antibody
      • mitochondrial antibody
      • NT5M antibody
      • NT5M_HUMAN antibody
      see all

    Anti-NT5M antibody images

    • Western blot against tagged recombinant protein immunogen using ab57518 NT5M antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-NT5M antibody (ab57518)

    ab57518 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57518.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"