Overview

  • Product nameAnti-NTH1 antibody
    See all NTH1 primary antibodies
  • Description
    Rabbit polyclonal to NTH1
  • SpecificityThis antibody is specific for NTH1.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide:

    CANRLWTKKATKSPE

    with a cysteine added for conjugation to KLH, corresponding to amino acids 237-249 of Human NTH1.

  • Positive control
    • K562 cell extracts , Hela cell extracts.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab93 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 37 kDa.

Target

  • FunctionHas both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.
  • Tissue specificityWidely expressed with highest levels in heart and lowest levels in lung and liver.
  • Sequence similaritiesBelongs to the Nth/MutY family.
  • Developmental stageExpression levels are regulated during the cell cycle with increased levels during early and mid S-phase.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bifunctional DNA N glycoslyase/DNA (apurinic or apyrimidinic site) lyase antibody
    • DNA glycoslyase/AP lyase antibody
    • Endonuclease III like protein 1 antibody
    • Endonuclease III-like protein 1 antibody
    • hNTH1 antibody
    • NTH 1 antibody
    • nth endonuclease III like 1 (E. coli) antibody
    • NTH endonuclease III Like 1 antibody
    • NTH1 antibody
    • NTHL 1 antibody
    • Nthl1 antibody
    • NTHL1_HUMAN antibody
    • OCTS 3 antibody
    • OCTS3 antibody
    see all

References for Anti-NTH1 antibody (ab93)

ab93 has not yet been referenced specifically in any publications.

Product Wall

We do not have any details on immunohistochemistry with this antibody. My guess is that it does not work well for that application as we have supporting IH data for the MTH1 and hOgg1 antibodies but nothing for the NTH1.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"