Anti-NUAK2 antibody - Aminoterminal end (ab71398)

Overview

  • Product name
    Anti-NUAK2 antibody - Aminoterminal end
    See all NUAK2 primary antibodies
  • Description
    Rabbit polyclonal to NUAK2 - Aminoterminal end
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the N-terminal region of human NUAK2.

  • Positive control
    • Transfected/ non-transfected 293 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab71398 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 80 kDa (predicted molecular weight: 70 kDa).
ELISA 1/1000.

Target

  • Function
    Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Phosphorylated at Thr-208 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Autophosphorylated in vitro.
  • Information by UniProt
  • Database links
  • Form
    Involved in actin cytoskeleton organization.
  • Alternative names
    • DKFZp434J037 antibody
    • DKFZp686F01113 antibody
    • FLJ90349 antibody
    • NUAK family SNF1 like kinase 2 antibody
    • NUAK family SNF1-like kinase 2 antibody
    • Nuak2 antibody
    • NUAK2_HUMAN antibody
    • Omphalocele kinase 2 antibody
    • SNARK antibody
    • SNF1/AMP activated protein kinase antibody
    • SNF1/AMP kinase related kinase antibody
    • SNF1/AMP kinase-related kinase antibody
    see all

Images

  • All lanes : Anti-NUAK2 antibody - Aminoterminal end (ab71398) at 1/50 dilution

    Lane 1 : Non-transfected 293 cell line lysates
    Lane 2 : NUAK2 transfected 293 cell line lysates

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 70 kDa
    Observed band size : 80 kDa (why is the actual band size different from the predicted?)

References

ab71398 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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