Anti-NUAK2 antibody - Aminoterminal end (ab71398)

Submit an Abreview Submit a Question

Overview

  • Product name
    Anti-NUAK2 antibody - Aminoterminal end
    See all NUAK2 primary antibodies
  • Description
    Rabbit polyclonal to NUAK2 - Aminoterminal end
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the N-terminal region of human NUAK2.

  • Positive control
    • Transfected/ non-transfected 293 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab71398 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 80 kDa (predicted molecular weight: 70 kDa).
ELISA 1/1000.

Target

  • Function
    Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Phosphorylated at Thr-208 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Autophosphorylated in vitro.
  • Information by UniProt
  • Database links
    • Form
      Involved in actin cytoskeleton organization.
    • Alternative names
      • DKFZp434J037 antibody
      • DKFZp686F01113 antibody
      • FLJ90349 antibody
      • NUAK family SNF1 like kinase 2 antibody
      • NUAK family SNF1-like kinase 2 antibody
      • Nuak2 antibody
      • NUAK2_HUMAN antibody
      • Omphalocele kinase 2 antibody
      • SNARK antibody
      • SNF1/AMP activated protein kinase antibody
      • SNF1/AMP kinase related kinase antibody
      • SNF1/AMP kinase-related kinase antibody
      see all

    Images

    • Western blot - NUAK2 antibody - Aminoterminal end (ab71398)
      Western blot - NUAK2 antibody - Aminoterminal end (ab71398)
      All lanes : Anti-NUAK2 antibody - Aminoterminal end (ab71398) at 1/50 dilution

      Lane 1 : Non-transfected 293 cell line lysates
      Lane 2 : NUAK2 transfected 293 cell line lysates

      Lysates/proteins at 2 µg per lane.

      Predicted band size: 70 kDa
      Observed band size: 80 kDa (why is the actual band size different from the predicted?)

    References

    ab71398 has not yet been referenced specifically in any publications.

    Publishing research using ab71398? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab71398.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up