The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 32 kDa.
Use at an assay dependent dilution.
Involvement in diseaseDefects in PNP are the cause of purine nucleoside phosphorylase deficiency (PNP deficiency) [MIM:613179]. It leads to a severe T-cell immunodeficiency with neurologic disorder in children.
Sequence similaritiesBelongs to the PNP/MTAP phosphorylase family.