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Rabbit polyclonal to Nucleoside phosphorylase
HumanPredicted to work with:
Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Saccharomyces cerevisiae
Synthetic peptide corresponding to a region within internal amino acids 108 - 157 (VDTLVVTNAA GGLNPKFEVG DIMLIRDHIN LPGFSGQNPL RGPNDERFGD) of Human Nucleoside phosphorylase (NP_000261)
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Involvement in disease
Defects in PNP are the cause of purine nucleoside phosphorylase deficiency (PNP deficiency) [MIM:613179]. It leads to a severe T-cell immunodeficiency with neurologic disorder in children.
Belongs to the PNP/MTAP phosphorylase family.
Cytoplasm > cytoskeleton.
Information by UniProt
- FLJ94043 antibody
- FLJ97288 antibody
- FLJ97312 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"