General notesDuring shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
FunctionMay be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis.
Tissue specificityIncreased levels in lung tissue in cancer patients.
Sequence similaritiesBelongs to the MMR1/HSR1 GTP-binding protein family. Contains 1 G (guanine nucleotide-binding) domain.
DomainThe basic domain (B) allows nucleolar localization in the absence of GTP. The intermediate domain (I) inhibits nucleolar localization by the B domain and is required for exit from the nucleolus. Exit from the nucleolus to the nucleoplasm requires both the I and the acidic (A) domains, and may be triggered by GTP hydrolysis. In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.
Cellular localizationNucleus. Nucleus > nucleolus. Shuttles between the nucleus and nucleolus.
Putative nucleotide binding protein estradiol induced antibody
Anti-Nucleostemin antibody images
Western blot - Anti-Nucleostemin antibody (ab14293)
Predicted band size : 66 kDa
E coli-derived fusion protein as test antigen. Affi-anti- RGS6 IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. Arrow points to E2IG3 fusion protein.
References for Anti-Nucleostemin antibody (ab14293)
has not yet been referenced specifically in any publications.
Publishing research using ab14293? Please let us know so that we can cite the reference in this datasheet.
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