Overview

  • Product nameAnti-Nucleostemin antibody
    See all Nucleostemin primary antibodies
  • Description
    Rabbit polyclonal to Nucleostemin
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A KLH conjugated synthetic peptide selected from the Center region of human Nucleostemin.

  • Positive control
    • HL60 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab64788 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 62 kDa (predicted molecular weight: 62 kDa).
ELISA 1/1000.

Target

  • FunctionMay be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis.
  • Tissue specificityIncreased levels in lung tissue in cancer patients.
  • Sequence similaritiesBelongs to the MMR1/HSR1 GTP-binding protein family.
    Contains 1 G (guanine nucleotide-binding) domain.
  • DomainThe basic domain (B) allows nucleolar localization in the absence of GTP. The intermediate domain (I) inhibits nucleolar localization by the B domain and is required for exit from the nucleolus. Exit from the nucleolus to the nucleoplasm requires both the I and the acidic (A) domains, and may be triggered by GTP hydrolysis.
    In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.
  • Cellular localizationNucleus. Nucleus > nucleolus. Shuttles between the nucleus and nucleolus.
  • Information by UniProt
  • Database links
  • Alternative names
    • C77032 antibody
    • E2 induced gene 3 protein antibody
    • E2-induced gene 3 protein antibody
    • E2IG3 antibody
    • Estradiol induced nucleotide binding protein antibody
    • GNL3 antibody
    • GNL3_HUMAN antibody
    • Guanine nucleotide binding protein like 3 (nucleolar) antibody
    • Guanine nucleotide binding protein like 3 antibody
    • Guanine nucleotide-binding protein-like 3 antibody
    • MGC800 antibody
    • NNP47 antibody
    • Novel nucleolar protein 47 antibody
    • NS antibody
    • Nucleolar GTP binding protein 3 antibody
    • Nucleolar GTP-binding protein 3 antibody
    • Nucleostemin antibody
    • Putative nucleotide binding protein estradiol induced antibody
    see all

Anti-Nucleostemin antibody images

  • Anti-Nucleostemin antibody (ab64788) at 1/60 dilution + HL60 cell line lysates at 35 µg

    Predicted band size : 62 kDa
    Observed band size : 62 kDa

References for Anti-Nucleostemin antibody (ab64788)

ab64788 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab64788.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"