Overview

  • Product nameAnti-NUDC antibody
    See all NUDC primary antibodies
  • Description
    Mouse monoclonal to NUDC
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-332 of Human NUDC

Properties

Applications

Our Abpromise guarantee covers the use of ab56999 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPlays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
    • Tissue specificityUbiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
    • Sequence similaritiesBelongs to the nudC family.
      Contains 1 CS domain.
    • Post-translational
      modifications
      Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases.
    • Cellular localizationCytoplasm > cytoskeleton. Nucleus. In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern.
    • Information by UniProt
    • Database links
    • Alternative names
      • HNUDC antibody
      • MNUDC antibody
      • MNUDC protein antibody
      • NPD011 antibody
      • Nuclear distribution C homolog antibody
      • Nuclear distribution gene C (A.nidulans) homolog antibody
      • Nuclear distribution gene C homolog antibody
      • Nuclear distribution gene C homolog (A. nidulans) antibody
      • Nuclear distribution protein C homolog antibody
      • Nuclear migration protein nudC antibody
      • nudC antibody
      • NudC nuclear distribution protein antibody
      • NUDC_HUMAN antibody
      • OTTHUMP00000004405 antibody
      • SIG 92 antibody
      • SIG92 antibody
      see all

    Anti-NUDC antibody images



    • Predicted band size : 38 kDa
      NUDC antibody (ab56999) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-NUDC antibody (ab56999)

    ab56999 has not yet been referenced specifically in any publications.

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