• Product nameAnti-NUDC antibody
    See all NUDC primary antibodies
  • Description
    Rabbit polyclonal to NUDC
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Cow, Cat, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide derived from within the sequence: EEDEEEDEKD KGKLKPNLGN GADLPNYRWT QTLSELDLAV PFCVNFRLKG , corresponding to amino acids 145 of Human NUDC

  • Positive control
    • HepG2 cell lysate



Our Abpromise guarantee covers the use of ab74792 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 38 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1:312500.


  • FunctionPlays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
  • Tissue specificityUbiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
  • Sequence similaritiesBelongs to the nudC family.
    Contains 1 CS domain.
  • Post-translational
    Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases.
  • Cellular localizationCytoplasm > cytoskeleton. Nucleus. In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern.
  • Information by UniProt
  • Database links
  • Alternative names
    • HNUDC antibody
    • MNUDC antibody
    • MNUDC protein antibody
    • NPD011 antibody
    • Nuclear distribution C homolog antibody
    • Nuclear distribution gene C (A.nidulans) homolog antibody
    • Nuclear distribution gene C homolog antibody
    • Nuclear distribution gene C homolog (A. nidulans) antibody
    • Nuclear distribution protein C homolog antibody
    • Nuclear migration protein nudC antibody
    • nudC antibody
    • NudC nuclear distribution protein antibody
    • NUDC_HUMAN antibody
    • OTTHUMP00000004405 antibody
    • SIG 92 antibody
    • SIG92 antibody
    see all

Anti-NUDC antibody images

  • Predicted band size : 38 kDa
    Western blot analysis of Jurkat cell lysate labeling NUDC with ab74792 at 1.0µg/ml.
  • Anti-NUDC antibody (ab74792) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 38 kDa
    Observed band size : 38 kDa

References for Anti-NUDC antibody (ab74792)

ab74792 has not yet been referenced specifically in any publications.

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