Overview

  • Product name
  • Description
    Goat polyclonal to Nup107
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Cow, Dog
  • Immunogen

    Synthetic peptide:

    PLPAEDDNAIREH

    by a Cysteine residue linker, corresponding to amino acids 735-747 of Human Nup107 (NP_065134.1)

  • Positive control
    • Peripheral Blood Lymphocyte lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab105026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 106 kDa.

Target

  • Function
    Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC.
  • Tissue specificity
    Ubiquitously expressed in fetal and adult tissues.
  • Involvement in disease
    Nephrotic syndrome 11
  • Sequence similarities
    Belongs to the nucleoporin Nup84/Nup107 family.
  • Cellular localization
    Nucleus membrane. Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755).
  • Information by UniProt
  • Database links
  • Alternative names
    • 107 kDa nucleoporin antibody
    • NU107_HUMAN antibody
    • Nuclear pore complex protein Nup107 antibody
    • Nucleoporin 107kDa antibody
    • Nucleoporin Nup107 antibody
    • NUP107 antibody
    • NUP84 antibody
    • NUP84, yeast, homolog of antibody
    • OTTHUMP00000240604 antibody
    • OTTHUMP00000240606 antibody
    see all

Images

  • Anti-Nup107 antibody (ab105026) at 2 µg + NIH3T3 nuclear cell lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 106 kDa
  • Anti-Nup107 antibody (ab105026) at 1 µg/ml + Peripheral Blood Lymphocytes lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 106 kDa


    Exposure time : 1 hour

References

ab105026 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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