Overview

  • Product name
  • Description
    Rabbit polyclonal to Nup107
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    A 20 amino acid synthetic peptide from near the center of Human Nup107.

  • Positive control
    • Human Skin tissue; A549 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab113913 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 106 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function
    Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC.
  • Tissue specificity
    Ubiquitously expressed in fetal and adult tissues.
  • Involvement in disease
    Nephrotic syndrome 11
  • Sequence similarities
    Belongs to the nucleoporin Nup84/Nup107 family.
  • Cellular localization
    Nucleus membrane. Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755).
  • Information by UniProt
  • Database links
  • Alternative names
    • 107 kDa nucleoporin antibody
    • NU107_HUMAN antibody
    • Nuclear pore complex protein Nup107 antibody
    • Nucleoporin 107kDa antibody
    • Nucleoporin Nup107 antibody
    • NUP107 antibody
    • NUP84 antibody
    • NUP84, yeast, homolog of antibody
    • OTTHUMP00000240604 antibody
    • OTTHUMP00000240606 antibody
    see all

Images

  • ab113913, at 5 µg/ml, staining Nup107 in formalin-fixed, paraffin-embedded Human Skin tissue by Immunohistochemistry.
  • Lane 1 : Anti-Nup107 antibody (ab113913) at 1 µg/ml
    Lane 2 : Anti-Nup107 antibody (ab113913) at 2 µg/ml

    Lane 1 : A549 cell lysate
    Lane 2 : A549 cell lysate


    Predicted band size : 106 kDa

References

ab113913 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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