Overview

  • Product name
    Anti-Nurr1 antibody [447C2a]
    See all Nurr1 primary antibodies
  • Description
    Mouse monoclonal [447C2a] to Nurr1
  • Tested applications
    Suitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Nurr1 recombinant fragment (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab54366 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Detects a band of approximately 37 kDa (predicted molecular weight: 66 kDa).
Dot blot Use at an assay dependent dilution.

Target

  • Function
    Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.
  • Tissue specificity
    Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.
  • Sequence similarities
    Belongs to the nuclear hormone receptor family. NR4 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Developmental stage
    Rapidly and only very transiently expressed after cell activation, during the G0-G1 transition of the cell cycle.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • HZF 3 antibody
    • HZF3 antibody
    • Immediate-early response protein NOT antibody
    • Intermediate early receptor protein antibody
    • NGFI B/nur77 beta type transcription factor homolog antibody
    • NOT antibody
    • Nr4a2 antibody
    • NR4A2_HUMAN antibody
    • nuclear receptor of T cells antibody
    • nuclear receptor related 1 antibody
    • Nuclear receptor subfamily 4 group A member 2 antibody
    • Nur related protein 1 homolog antibody
    • nur related protein-1, human homolog of antibody
    • Nurr 1 antibody
    • Orphan nuclear receptor NR4A2 antibody
    • Orphan nuclear receptor NURR1 antibody
    • RNR 1 antibody
    • RNR1 antibody
    • T cell nuclear receptor NOT antibody
    • T-cell nuclear receptor NOT antibody
    • TINUR antibody
    • Transcriptionally inducible nuclear receptor antibody
    • Transcriptionally inducible nuclear receptor related antibody
    • Transcriptionally inducible nuclear receptor related 1 antibody
    • Transcriptionally-inducible nuclear receptor antibody
    see all

Images

References

ab54366 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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