1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
1/100 - 1/1000.
May function as a tissue-specific nuclear mRNA export factor.
Expressed at high level in testis and at low level in a small number of tissues.
Belongs to the NXF family. Contains 1 NTF2 domain. Contains 1 RRM (RNA recognition motif) domain.
Lacks C-terminal domain that mediates direct interactions with nucleoporins. Contains a novel CRM1-dependent nuclear export signal that compensates in cis for the loss of the nuclear pore targeting domain. The RNA-binding domain is a non-canonical RNP-type domain.
Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm.