Overview

  • Product nameAnti-NYREN18 antibody
    See all NYREN18 primary antibodies
  • Description
    Rabbit polyclonal to NYREN18
  • Tested applicationsSuitable for: IHC-P, ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, selected from within C terminal amino acids 500-550 of Human NYREN18.

  • Positive control
    • HEK 293 cell lysate, Human breast carcinoma tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesThis antibody was purified through a protein G column and eluted out with both high and low pH buffers. It was neutralized immediately after elution, followed by dialysis against PBS.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab38437 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 69 kDa (predicted molecular weight: 69 kDa).

Target

  • FunctionSpecific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
  • Tissue specificityWidely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.
  • Sequence similaritiesContains 3 UBA domains.
  • Cellular localizationNucleus. Predominantly nuclear.
  • Information by UniProt
  • Database links
  • Alternative names
    • BS4 antibody
    • NEDD8 ultimate buster 1 antibody
    • Negative regulator of ubiquitin like proteins 1 antibody
    • Negative regulator of ubiquitin-like proteins 1 antibody
    • NUB1 antibody
    • NUB1_HUMAN antibody
    • NUB1L antibody
    • NY REN 18 antibody
    • NYREN18 antibody
    • Renal carcinoma antigen NY-REN-18 antibody
    see all

Anti-NYREN18 antibody images

  • Anti-NYREN18 antibody (ab38437) at 1/100 dilution + HEK 293 cell lysate

    Predicted band size : 69 kDa
    Observed band size : 69 kDa
  • ab38437 staining NYREN18 in Human breast carcinoma tissue by Immunohistochemistry, Formalin fixed Paraffin embedded section. ab38437 was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

References for Anti-NYREN18 antibody (ab38437)

ab38437 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"