Purification notesThis antibody was purified through a protein G column and eluted out with both high and low pH buffers. It was neutralized immediately after elution, followed by dialysis against PBS.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100.
1/100 - 1/500. Detects a band of approximately 69 kDa (predicted molecular weight: 69 kDa).
FunctionSpecific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
Tissue specificityWidely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.
ab38437 staining NYREN18 in Human breast carcinoma tissue by Immunohistochemistry, Formalin fixed Paraffin embedded section. ab38437 was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
References for Anti-NYREN18 antibody (ab38437)
has not yet been referenced specifically in any publications.
Publishing research using ab38437? Please let us know so that we can cite the reference in this datasheet.
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