For the best experience on the Abcam website please upgrade to a modern browser such as
Rabbit polyclonal to NYREN18
Synthetic peptide conjugated to KLH selected within aa 100~125 of human NYREN18.
Mouse liver lysate.
Human hepatocarcinoma tissue.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Preservative: 0.09% Sodium Azide
Concentration information loading...
Protein G purified
This antibody is purified through a protein G column, eluted out with both high and low pH buffers, neutralized immediately after elution then followed by dialysis against PBS.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa).
1/50 - 1/100.
Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.
Contains 3 UBA domains.
Nucleus. Predominantly nuclear.
Information by UniProt
NEDD8 ultimate buster 1 antibody
Negative regulator of ubiquitin like proteins 1 antibody
Western blot - NYREN18 antibody (ab38438)
Anti-NYREN18 antibody (ab38438) at 1/100 dilution + Mouse liver lysate
Predicted band size: 71 kDa Observed band size: 71 kDa Additional bands at: 14 kDa, 23 kDa, 30 kDa, 45 kDa. We are unsure as to the identity of these extra bands.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - NYREN18 antibody (ab38438)
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ab38438, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"