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Rabbit polyclonal to NYREN18
Synthetic peptide conjugated to KLH selected within aa 100~125 of human NYREN18.
Mouse liver lysate.
Human hepatocarcinoma tissue.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Preservative: 0.09% Sodium Azide
Concentration information loading...
Protein G purified
This antibody is purified through a protein G column, eluted out with both high and low pH buffers, neutralized immediately after elution then followed by dialysis against PBS.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa).
1/50 - 1/100.
Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.
Contains 3 UBA domains.
Nucleus. Predominantly nuclear.
Information by UniProt
NEDD8 ultimate buster 1 antibody
Negative regulator of ubiquitin like proteins 1 antibody
Western blot - Anti-NYREN18 antibody (ab38438)
Anti-NYREN18 antibody (ab38438) at 1/100 dilution + Mouse liver lysate
Predicted band size: 71 kDa Observed band size: 71 kDa Additional bands at: 14 kDa, 23 kDa, 30 kDa, 45 kDa. We are unsure as to the identity of these extra bands.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NYREN18 antibody (ab38438)
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ab38438, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining
has not yet been referenced specifically in any publications.
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