Overview

  • Product name
  • Description
    Goat polyclonal to OAS2
  • Host species
    Goat
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human OAS2 aa 357-371 (internal sequence). (NP_058197.2).
    Sequence:

    QPNKCFLEQIDSAVN


    Database link: P29728

  • Positive control
    • Human breast tissue; Daudi, K562 and Jurkat cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab195968 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 82, 79 kDa).

Target

  • Function
    May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis.
  • Sequence similarities
    Belongs to the 2-5A synthase family.
  • Cellular localization
    Mitochondrion. Nucleus. Microsome. Endoplasmic reticulum. Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
  • Information by UniProt
  • Database links
  • Alternative names
    • (2-5'')oligo(A) synthase 2 antibody
    • (2-5')oligo(A) synthetase 2 antibody
    • 2''-5''-oligoadenylate synthase 2 antibody
    • 2'-5'-oligoadenylate synthetase 2 antibody
    • 2'-5'-oligoadenylate synthetase 2, 69/71kDa antibody
    • 2-5A synthase 2 antibody
    • 2-5A synthetase 2 antibody
    • 2-prime, 5-prime-oligoadenylate synthetase 2 edit item name - 2-prime, 5-prime-oligoadenylate synthetase 2, 69-KD antibody
    • 2-prime, 5-prime-oligoadenylate synthetase 2 antibody
    • MGC78578 antibody
    • OAS2 antibody
    • OAS2_HUMAN antibody
    • p69 antibody
    • p69 OAS / p71 OAS antibody
    • p69OAS / p71OAS antibody
    see all

Images

  • All lanes : Anti-OAS2 antibody (ab195968) at 0.3 µg/ml

    Lane 1 : Daudi cell lysate (in RIPA buffer)
    Lane 2 : Jurkat cell lysate (in RIPA buffer)
    Lane 3 : K562 cell lysate (in RIPA buffer)

    Lysates/proteins at 35 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 82, 79 kDa
    Observed band size: 70 kDa (why is the actual band size different from the predicted?)



    Primary incubation was 1 hour.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human breast tissue labeling OAS2 with ab195968 at 5 µg/ml.

References

ab195968 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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